The vaccine contains fragments of coronavirus spike proteins and is delivered in three doses: two injections and one nasal spray. PHASE 3 EFFICACY TRIALS: Scientists give the vaccine to thousands of people and wait to see how many become infected, compared with volunteers who received a placebo. Storage: Refrigerated *Includes people vaccinated in the states, territories and three countries with special agreements with the United States: Palau, Micronesia and the Marshall Islands. They deliver virus genes into leaves, and the plant cells then create protein shells that mimic viruses.In July, Medicago launched Phase 1 trials on a plant-based Covid-19 vaccine in combination with adjuvants to boost the immune system’s response to the viral proteins. On June 30, the Japanese biotechnology company AnGes launched a Phase 1 trial to test a DNA-based vaccine, developed in partnership with Osaka University and Takara Bio. February 27, 2021 . The vaccine was previously authorized for people 16 and older. Updated May 6, PHASE 1 New York City broke down its Covid-19 vaccination data by ethnicity for the first time, with the mayor underscoring a “profound problem” with racial inequality. Making matters murkier, they gave different amounts of the vaccine to different people and also waited anywhere from four to twelve weeks to deliver the second dose.On Dec. 8, AstraZeneca and Oxford published the first scientific paper on a Phase 3 clinical trial of a coronavirus vaccine. Limited use in: United Arab Emirates. Dose: 3 doses, 4 weeks apart New York Times shows where you might fall in line for COVID-19 vaccine - KAKE Endorsed by the Africa Regulatory Taskforce NEW. In January Sanofi decided to help Pfizer and BioNTech make 100 million doses of their vaccine, and they reached a similar agreement with Johnson & Johnson in February.Meanwhile, Sanofi developed a stronger formulation of their own vaccine. The spike protein provokes the body to make antibodies, while the pieces of other proteins train the immune system to recognize infected cells and kill them.In addition, the researchers created an RNA molecule with the same genetic instructions, which they put in a shell. We reached this milestone a few days after some other trackers because—unlike many trackers—we compile deaths only from New York State and not directly from NYC. Shafa Pharmed Pars, an Iranian pharmaceutical company, developed a vaccine made of inactivated coronaviruses. At least 77 preclinical vaccines are under active investigation in animals. They then inserted this cassette into the genes of a chimpanzee adenovirus. of all residents that are fully vaccinated, Pct. The company announced that its one-shot vaccine had an efficacy rate of 65.28 percent at preventing all symptomatic Covid-19 cases. Community. In December, CureVac launched a Phase 3 trial, recruiting up to 36,500 volunteers in Germany. Phase 3 trials are also large enough to reveal evidence of relatively rare side effects. But Finlay researchers are specifically tailoring this vaccine to people who have already had Covid-19 — a first of its kind. It was the first time anyone had found such evidence. No one in the Brazil trial who received Sinovac had to be hospitalized.Sinovac has struck deals with at least 11 countries and regions to supply them with SinoVac. The CDC data on doses delivered reflects the total number of doses reserved for New York State to date, inclusive of doses scheduled for shipment to New York State for the … The researchers created the vaccine from a mixture of proteins. The researchers have found that the Covid-19 vaccine produces antibodies in mice.The Indian company Biological E licensed it in August and launched a Phase 1/2 trial in November, combining the viral proteins with an adjuvant made by Dynavax. The researchers registered a Phase 1 trial in Australia on Feb. 8. Updated March 9, PHASE 2 The Institute of Vaccines and Medical Biologicals in Vietnam has done the same. The vaccine is now in a Phase 2/3 trial. Last May, they launched a Phase 1 trial on 192 volunteers which indicated the vaccine was safe and produced an immune response. CureVac has collaborated with Elon Musk’s company Tesla on creating mRNA “micro-factories,” which could potentially be deployed around the world to make billions of doses of the vaccine. The vaccine is based on a coronavirus protein which is produced in insect cells by genetically altered viruses. Updated May 3, PHASE 2 PHASE 3 COMBINED PHASES South Africa dropped plans to use AstraZeneca’s vaccine for their health care workers after a small trial failed to show it was effective against the B.1.351 variant that had grown dominant across the country. Johnson & Johnson used Ad26 to develop vaccines for Ebola and other diseases with Ad26. In South Africa, a small trial failed to demonstrate that it protected people against the variant B.1.351, which has become predominant in the country. Experts have warned of serious risks from jumping ahead of these results. Clover Biopharmaceuticals developed a vaccine containing the spike protein from coronaviruses. Storage: Over a year at room temperature They have now used it to make a nasal spray vaccine for Covid-19, delivering the Ad5 adenovirus to the airway. The federal data may differ from that reported by states and territories, which may post on different schedules. It was based on vesicular stomatitis viruses, the same approach Merck successfully used to produce the first approved vaccine for Ebola. The development cycle of a vaccine, from lab to clinic. A 30,000-person Phase 3 trial in the United States was delayed because of problems with manufacturing the doses required for the study. In response some countries chose to minimize the risk by restricting Vaxzevria to older people.The United States has not yet authorized Vaxzevria, despite the lavish support it provided for its development. On Feb. 18, Novavax announced it would supply 1.1 billion doses to COVAX, a consortium that seeks to distribute vaccines to all countries across the world.On May 3, the company expanded its U.S. Scientific and Technological Research Council of Turkey, the first to put a Covid-19 vaccine into human trials, published the results of their Phase 3 trial, They began using Johnson & Johnson’s instead, the effects of two doses of their vaccine, faced delays in recruiting enough participants for their Phase 1 study, Covid-19 vaccine based on a virus called Newcastle Disease Virus, Institute of Vaccines and Medical Biologicals, 96 percent against the original coronavirus. COVID-eVax can remain stable at room temperature. Hot spots like Michigan are seeing improvement in case counts too, according to the New York Times coronavirus tracker. Updated Jan. 24, PHASE 2 They project manufacturing up to 300 million doses in 2021 and up to a billion doses the following year. The company developed it in collaboration with the National Institute of Infectious Diseases and Kyushu University. In early 2020, Imperial College London researchers developed a “self-amplifying” RNA vaccine for Covid-19, which boosted production of a viral protein to stimulate the immune system. Updated May 5, PHASE 3 Michiana Eats. They have created and tested pills for influenza and other diseases. If the trial proved successful, the vaccine would be produced by the Iranian company CinnaGen. Efficacy: 91.3% In July 2020, the Indian vaccine-maker Zydus Cadila began testing a DNA-based vaccine delivered by a skin patch. On Oct. 25, the Israeli government announced that the vaccine, called Brilife, would be going into a Phase 1 trial. Vaccine name: COVAC A team of Turkish researchers at Middle East Technical University and Bilkent University have developed a vaccine that is made up of virus-like particles. But researchers are testing one therapy that may help: monoclonal antibodies. Among that group, 36.4% are fully vaccinated, meaning they have either received both shots of a … On April 22, Valneva launched a Phase 3 trial on 4,000 volunteers in the United Kingdom. AstraZeneca and Oxford then embarked on late-stage trials in the United Kingdom, South Africa, and elsewhere. Those numbers may be … Turkey authorized the vaccine on Jan. 13, and its president got vaccinated the next day. The researchers picked these proteins because they have a low chance of mutating — a feature that, they say, that makes the vaccine “variant-proof.” Efficacy: 65.28% The European Union began a rolling review in February, intended to speed up approval if the Phase 3 trial delivers positive results. When the bacteria reach the intestines, the DNA slips into cells in the gut lining, which then make viral proteins. Type: Muscle injection Merck and IAVI received $38 million from the United States government to support their research, and on September 30 they registered a Phase 1 trial. PHASE 3 In June, The New York Times reported, a hedge fund that partly controlled the company sold off most of its shares, netting over $200 million in profits. CDC’s home for COVID-19 data. After positive results from a Phase 1 trial, Finlay received approval to begin a Phase 2 trial among Covid-19 survivors on April 9. Moderna’s vaccine is one of several being tested in an Oxford study that gauges how well alternating doses can boost immunity.For more details, see How Moderna’s Vaccine Works. Cuba’s Finlay Vaccine Institute developed a vaccine known as Soberana 2. On April 28, they registered a Phase 1/2 trial of the vaccine in Japan. But supply chain issues have forced Novavax to push back its predictions. Researchers began dosing trial participants in Iran on April 26. Dallas-based Vaxxinity is testing a vaccine containing parts of several viral proteins. It was scheduled to begin the following month. Storage: Stable at least 3 months at 36–46°F (2–8°C) It registered a Phase 2/3 trial with the GSK adjuvant, but in February the company announced it was cancelling the study. A study published in May demonstrated that Comirnaty was somewhat less effective against some variants, but still provided strong protection.Comirnaty is currently being tested in a number of additional trials. New York State’s Vaccine Tracker includes all weekly dose allocations fully received by New York State providers. The California-based company Arcturus Therapeutics and Duke-NUS Medical School in Singapore have developed an mRNA vaccine. The researchers thought that the antibodies would not grab the clamp. In early 2021, trials in Brazil and Turkey showed that it could protect against Covid-19, but they delivered strikingly different results — in part because they designed the trials differently. Along with their Beijing Institute vaccine, Sinopharm also tested an inactivated virus vaccine developed by the Wuhan Institute of Biological Products. Data not updated on some weekends and holidays. Efficacy: Unknown On Jan. 20, the company registered a Phase 1/2 trial. The vaccine is based on a combination of two strains of adenoviruses, called Ad5 and Ad35. On Feb. 1, the center held a press conference to announce the start of a Phase 2 trial. reported about 4.6 million new doses administered, including about 1.6 million doses that were reported after the 6 a.m. cutoff, resulting in a visible spike. notes that total doses administered are based on the location where the vaccine was given, and that in limited cases, people might get a vaccine outside of their place of residency. In February they added a Phase 2 trial to a U.S. registry, where they indicated the trial included 1,000 people and that the study would be completed by the end of the month. Approved for use in: China. Updated June 23, PHASE 3 The company later registered a Phase 3 trial to begin May 2021. NY has the highest per capita hospitalizations in the country right now, with 338 per million people. Type: Muscle injection On March 22, Japan’s KM Biologics announced that it had begun a Phase 1/2 trial of its inactivated vaccine candidate, called KD-414. Contests. In December, federal regulators gave emergency use authorization to two-dose vaccines developed by Pfizer-BioNTech and Moderna. In addition, some countries such as China and Russia began administering vaccines before detailed Phase 3 trial data was made public. Last March, the Trump administration unsuccessfully tried to entice CureVac to move its research on their mRNA vaccine from Germany to the United States. They produced the proteins with engineered viruses that grow inside insect cells. After the SARS epidemic in 2002, Baylor College of Medicine researchers began developing a vaccine that could prevent a new outbreak. On March 16, Iran’s Ministry of Defence announced another vaccine made of inactivated coronaviruses. Although Johnson & Johnson initially set out to recruit 60,000 volunteers, it capped the trial at 45,000 in December as cases rose.On Jan. 29, Johnson & Johnson announced that the trial had proven that the vaccine was safe and effective, and the F.D.A. The New York Times used vaccine tools developed by the Surgo Foundation and Ariadne Labs to make the predictions. In July, Sinovac launched a Phase 3 trial in Brazil, followed by others in Indonesia and Turkey. By combining them, the Russian researchers hoped to avoid a situation in which the immune system could learn to recognize the vaccine as a foreign object that needed to be destroyed. Once the shell slips into a cell, the RNA molecule can make copies of itself, and the cell then makes proteins from those copies.In a Phase 1 trial launched in March, the National Institute of Allergy and Infectious Diseases is testing how well these two vaccines work together, with the chimpanzee adenovirus serving as the first dose and the self-amplifying RNA as the second. On April 5, the army launched a Phase 1 trial. But on Jan. 25, they announced they were abandoning the effort because the vaccine failed to trigger an immune system comparable to what happens in a natural infection of Covid-19. On Feb. 22, the company launched a new Phase 2 trial. As a result, our prediction of when the country will achieve herd immunity—a nebulous figure to begin with that was pegged somewhere around 70% or higher—has been pushed from July to August. Now that the United States has enough vaccines from other companies to protect all its own citizens, there are calls to ship AstraZeneca’s vaccines to India and other countries in dire need. The Italian biotechnology company ReiThera has developed a Covid-19 vaccine, called GRAd-COV2, that is based on an adenovirus that infects gorillas. On Jan. 25, Merck announced it was abandoning the effort, because the vaccine provoked a response that was weaker than a natural infection. On Nov. 11, the Russian Direct Investment Fund announced the first preliminary evidence from their Phase 3 trial indicating that the vaccine is effective. Stopped use in: Denmark. The New York Times: F.D.A. Efficacy: Unknown expanded the authorization to children as young as 12.The work on the vaccine began in January 2020, when BioNTech researchers started fashioning a genetic molecule called messenger RNA (mRNA). Emergency use in: Canada, European Union, Greenland, Guatemala, Honduras, Iceland, Israel, Kuwait, Mongolia, Norway, Qatar, Singapore, United Kingdom, United States, Vietnam. In addition to their Abdala vaccine, the Center for Genetic Engineering and Biotechnology of Cuba announced on Nov. 26 that it was beginning a Phase 1 trial of a second vaccine, this one delivered as a nasal spray. Additional reporting by Farnaz Fassihi, Denise Grady, Andrew E. Kramer, Matthew Kristoffersen, Hari Kumar, Cao Li, Jess Ruderman and Carlos Tejada. ... New York COVID-19 Vaccine Tracker. The Phase 2 trial, which is recruiting up to 1,000 volunteers, started on Jan. 5. They launched a Phase 2 trial on ZyCoV-D on Aug. 6 and announced at the end of December that it was complete. At least 15 million doses of Johnson & Johnson’s vaccine were contaminated at the factory. In addition to their mRNA vaccine, Sanofi developed a Covid-19 vaccine based on viral proteins in early 2020. Tests on animals showed that it protected them against infection. Updated May 1, PHASE 2 There are many reasons eligible people may not be vaccinated, including, in some areas, lingering issues of short supply, limited access to vaccination sites and confusing procedures for booking appointments. The final analysis of Covaxin’s safety and efficacy is expected in June.In April, India saw a surge of new cases, many of which were caused by a new variant called B.1.617. EMERGENCY USE IN OTHER COUNTRIES began including shots given by the federal agencies in each state’s count. Storage: Freezer storage. issued a scathing report about the company’s lax standards. Updated April 26, PHASE 2 Updated Feb. 23, PHASE 1 PHASE 2 COMBINED PHASES The Global Times reported that the trial would likely be run in Latin America. While the pill produced a response from T cells, it didn’t produce encouraging neutralizing antibodies. The trial delivered encouraging results: volunteers produced a high level of antibodies with no evidence of harmful side effects.But then the researchers made an unwelcome discovery: some volunteers were getting positive tests for HIV, even though they were not actually infected with that virus. The COVID-19 vaccine is now available in NYC to all U.S. residents 16 and older. EARLY OR LIMITED APPROVAL: Many countries have procedures for providing emergency authorizations for vaccines, based on preliminary evidence that they are safe and effective. To notify The Times of new developments, send updates to vaccinetracker@nytimes.com. Updated Dec. 17, PHASE 1 The university launched a Phase 1 trial in July, combining coronavirus spike proteins with an adjuvant made by CSL. Storage: 30 days with refrigeration, 6 months at –4°F (–20°C) APPROVED IN CHINA On Dec. 18., the F.D.A. APPROVED IN CHINA, BAHRAIN, U.A.E. COVAX, an international collaboration to deliver the vaccine equitably across the world, secured 500 million doses. After a series of promising experiments on animals, they began injecting volunteers for a Phase 1 trial in early October. In October Shenzhen Kangtai launched a Phase 1 trial on 180 volunteers of its own vaccine, based on inactivated coronaviruses. The French vaccine maker Valneva created a vaccine from chemically inactivated coronaviruses, using an adjuvant from Dynavax. In March, ... Photo: The New York Times/Redux. On March 24, they advanced the vaccine to Phase 2. Efficacy: More than 90% Counties are ranked according to the Social Vulnerability Index, a C.D.C. Among women between the ages of 30-39, the rate is 12.4 cases per million doses. Africa; Americas; South-East Asia; Europe; Eastern Mediterranean; Western Pacific; About us . But the presence of more transmissible virus variants could complicate that progress. A Phase 2/3 trial of the vaccine began on Nov. 12. Recommended Stories . PRECLINICAL TESTING: Scientists test a new vaccine on cells and then give it to animals such as mice or monkeys to see if it produces an immune response. On Feb. 3, Vaxart announced that the trial revealed no serious safety concerns. Studies on monkeys and hamsters found that it provided protection against infection. March 15, 2021, 2:29 PM. In April 2021, the F.D.A. gave emergency approval for Sinopharm’s vaccine to use on health care workers, and soon government officials and others were also receiving it. Vaccine experts decried the move as risky, and Russia later walked back the announcement, saying that the approval was a “conditional registration certificate,” which would depend on positive results from Phase 3 trials. It’s not clear how the trial will fare now that Israel is aggressively vaccinating its citizens with authorized vaccines by Pfizer. Clover’s formula looks to be especially durable; the vaccine can sit out at room temperature for a month and remain viable.Clover launched a Phase 1 trial last June, and in December the company announced that the vaccine triggered a high level of antibodies. The comments section is closed. If trials proceed as expected, researchers predict that at least one of their candidates will be ready by late 2021. The Telegraph. As a result, NDV-HXP-S could be very cheap to make. The vaccine has completed a Phase 1 trial and will begin Phase 2 after Ramadan, the Tehran Times reported on May 5. The COVID-19 vaccine is now available in NYC to all U.S. residents 16 and older. Stopped use in Denmark. Updated May 7, PHASE 3 But in South Africa, where volunteers were exposed to the variant B.1.351, the efficacy was only 49 percent. On Dec. 30, Medigen announced that it had received permission to commence a Phase 2 trial. Bourla, the chief executive, said people would “likely” need an additional shot of its vaccine within a year of receiving two doses. A cease-and-desist letter from August obtained by The New York Times shows Tiffany Tate, creator of vaccination tracker PrepMod, is seeking $15 million in … When all adults became eligible for the vaccine in each state, Texas Department of State Health Services, recommended use of the Pfizer-BioNTech vaccine, Centers for Disease Control and Prevention, blood clots in a small number of patients, analyzed vaccine records and voter records, Frequently Asked Questions About the Covid Data. reports the number of people receiving one or more doses based on where individuals reside. Updated Sept. 24, PHASE 1 PHASE 2 COMBINED PHASES Last June, Covaxin became the first coronavirus vaccine created in India to go into clinical trials.The phase 1/2 trial showed that the vaccine didn’t cause any serious side effects while producing antibodies to the coronavirus, and a follow-up study confirmed these results. The trial will determine whether the vaccine provides as much protection for them as for women who aren’t pregnant, and also gather information on its safety. In October 2020, Entos launched a Phase 1 trial in Canada for their vaccine, called Covigenix VAX-001. to receive this information. They then grew the modified virus in chicken eggs. In March, the company began testing the vaccine in babies and young children.Meanwhile, the company entered deals with several countries to supply the vaccine pending its approval. In addition to delivering vaccines to states, territories and some federal agencies, the C.D.C. The New York Times created an online quiz where you can find your place in the "Vaccine Line". The Biden administration has also committed to distributing shots equitably to the communities most affected by the pandemic. Many cannot produce enough infection-fighting cells to fend off the coronavirus. Takis Biotech and Rottapharm Biotech, two vaccine companies in Italy, developed a vaccine called COVID-eVax. Efficacy: 50.65% in Brazil trial, 91.25% in Turkey trial Sinopharm started a Phase 1/2 trial on April 24. In November, they announced that the vaccine was well tolerated and produced antibodies, and released a report on the trial in April 2021. PHASE 2 EXPANDED TRIALS: Scientists give the vaccine to hundreds of people split into groups, such as children and the elderly, to see if the vaccine acts differently in them. The researchers engineered NDV to carry the gene for a modified version of the coronavirus spike protein called HexaPro, developed at the University of Texas. Researchers at China’s Sinopharm have created a protein-based vaccine that uses a genetically engineered spike protein to help the body produce antibodies. New York reported 2,075,539 total cases of coronavirus, an increase of 0.78% from the week before. ImmunityBio launched a Phase 1 trial of a Covid-19 vaccine in October in the United States and another in South Africa in January. This resulted in a decrease for Washington, D.C. Are The Most Vulnerable Counties Being Vaccinated? gave full approval to BBIBP-CorV, announcing it had an efficacy rate of 86 percent. Updated May 10. The vaccine, called VBI-2902a, is a combination of protein shells and aluminum phosphate as an adjuvant.VBI Vaccines is also experimenting with vaccines that combine proteins from the three coronaviruses that cause severe disease in humans: Covid-19, SARS, and MERS. Dose: To be determined Updated March 20, PHASE 1 PHASE 2 COMBINED PHASES EMERGENCY USE IN U.S., ELSEWHERE However, it’s unlikely that the vaccine will be significantly less effective against it.In April, Covaxin announced it was ramping up its production to 700 million doses a year.For more details, see How Bharat Biotech’s Vaccine Works. In October, authorities in the eastern Chinese city of Jiaxing announced they were giving CoronaVac to people in relatively high-risk jobs, including medical workers, port inspectors and public service personnel.The scientists running the Phase 3 trials began announcing early results at the end of December and continued to update them as new cases of Covid-19 arose. (Vaxxinity formed in April 2021 when the companies COVAXX and United Neuroscience combined.) Updated May 5, PHASE 1 As talk has swirled about immunity passports and ID systems for vaccine tracking, anxieties and conspiracy theories have as well. The first volunteers in the trial were injected in late January. The Chinese company CanSino Biologics developed Convidecia in partnership with the Institute of Biology at the country’s Academy of Military Medical Sciences. South Korean vaccine producer EuBiologics launched a Phase 1/2 trial of a protein-based vaccine in late January. Type: Skin injection Gamaleya produced the vaccine, initially called Gam-Covid-Vac, from a combination of two adenoviruses called Ad5 and Ad26. Regulators authorized Johnson & Johnson’s one-dose vaccine in February, but recommended a pause in its use on April 13 because of reports of blood clots in a small number of patients. The American company Merck acquired the Austrian firm Themis Bioscience in June to develop their vaccine, which had been originally developed at Institut Pasteur. Approved for use in: China. Storage: Freezer storage only at –13°F to 5°F (–25°C to –15°C) On Feb. 16 the World Health Organization recommended the vaccine for emergency use in adults 18 or older. Vaccine name: ZyCoV-D Approved for use in: China. Notes and corrections: Early versions of the tracker combined two vaccines by Sinopharm into one entry, before subsequent reporting confirmed they were two different vaccines. Trackers. Despite promising early results, support for the research disappeared. Comirnaty is also one of several vaccines being tested in an Oxford study to gauge how well alternating doses promote immunity.Dr. Updated Dec. 14, PHASE 1 The researchers commenced a Phase 3 trial In March, Kazakhstan’s vice minister of education and science announced that the vaccine, known as QazVac, was expected to be authorized in April, despite the lack of published results from the Phase 3 trial.Kazakhstan began administering its vaccine to the public in late April. The process is expected to take several months.As the trials progressed, Pfizer and BioNTech also scaled up factories to produce Comirnaty in huge amounts. PHASE 3 In March the companies launched a Phase 1/2 trial, which they anticipate delivering results in the third quarter of 2021. Havana, Sep 8 - Cuban vaccine candidate Soberana 01 appears in the Covid-19 vaccine tracker on the US newspaper The New York Times website, Infomed reported today. Researchers rewrite the genome of viruses, introducing hundreds of mutations. They began using Johnson & Johnson’s instead.In August 2020, the federal government agreed to pay Johnson & Johnson $1 billion for 100 million doses if the vaccine was authorized. Updated April 20, PHASE 1 PHASE 2 COMBINED PHASES But the researchers ran the trials independently, making it difficult to combine their results into a single clear picture of how well the vaccine worked. Dose: 2 doses, 4 weeks apart By Carl Zimmer, Jonathan Corum and Sui-Lee WeeUpdated May 15, 2021. On Sept. 9, they received approval to start clinical trials in partnership with Beijing Wantai Biological Pharmacy. Last January, the company and Beth Israel researchers collaborated on creating a coronavirus vaccine. The one-shot vaccine is based on an adenovirus called Ad5. In an interview with the Bangkok Post, the leader of the project said that up to 30 million doses might be produced for Thailand and six other Asian countries if the vaccine proved to be safe and effective. Sinopharm’s two other vaccine candidates, one developed with the Beijing Institute and one developed with the Wuhan Institute, use inactivated coronaviruses to develop immunity. began reporting county-level vaccinations on March 26. 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